Mizukami M, Yamaguchi K, Yunoki K
Stroke. 1981 Nov-Dec;12(6):793-8. doi: 10.1161/01.str.12.6.793.
Eighty-four patients with cerebrovascular disease were studied by cerebral angiography and a prototype Doppler device, ultrasonic quantitative flow measurement (UQFM), that provides data from which absolute common carotid flow can be determined. The UQFM showed significantly lower flows in 23 patients who had complete occlusion of the internal carotid artery on the affected side (p less than 0.001). In 11 patients with occlusion of hte middle cerebral artery at its origin and in 5 with branch occlusions, the blood flow in the ipsilateral common carotid artery was also significantly lower (p less than 0.01). There was no significant difference between blood flow on the 2 sides in 9 patients with stenosis of middle cerebral artery and in 7 with stenosis of internal carotid artery. Due to the small number of patients no definite conclusion can be drawn. The UQFM is thought to be useful not only in screening for occlusive cerebrovascular disease but also to help understand better the mechanisms of ischemia in the presence of carotid lesions.
对84例脑血管疾病患者进行了脑血管造影和一种原型多普勒设备——超声定量血流测量仪（UQFM）的研究，该设备可提供能确定颈总动脉绝对血流量的数据。UQFM显示，23例患侧颈内动脉完全闭塞的患者血流量显著降低（p<0.001）。在11例大脑中动脉起始部闭塞和5例分支闭塞的患者中，同侧颈总动脉的血流量也显著降低（p<0.01）。9例大脑中动脉狭窄和7例颈内动脉狭窄的患者两侧血流量无显著差异。由于患者数量较少，无法得出明确结论。UQFM被认为不仅有助于筛查闭塞性脑血管疾病，还能更好地理解颈动脉病变时的缺血机制。
