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The incorporation of 5-fluoro-2'-deoxyuridine into DNA of mammalian tumor cells.

作者信息

Danenberg P V, Heidelberger C, Mulkins M A, Peterson A R

出版信息

Biochem Biophys Res Commun. 1981 Sep 30;102(2):654-8. doi: 10.1016/s0006-291x(81)80182-9.

DOI:10.1016/s0006-291x(81)80182-9
PMID:6458299
Abstract
摘要

相似文献

1
The incorporation of 5-fluoro-2'-deoxyuridine into DNA of mammalian tumor cells.
Biochem Biophys Res Commun. 1981 Sep 30;102(2):654-8. doi: 10.1016/s0006-291x(81)80182-9.
2
5-Fluoro-2'-deoxyuridine incorporation in L1210 DNA.5-氟-2'-脱氧尿苷掺入L1210 DNA中。
J Biol Chem. 1981 Sep 10;256(17):8885-8.
3
Cytotoxicity of 5-fluoro-5'-O-nitro-2'-deoxyuridine, a new fluorinated pyrimidine derivative, in L1210 cultures.新型氟化嘧啶衍生物5-氟-5'-O-硝基-2'-脱氧尿苷在L1210细胞培养中的细胞毒性
Mol Pharmacol. 1982 Nov;22(3):760-5.
4
5-Fluoro-5'-deoxyuridine is an inhibitor of uridylate nucleotidase in L1210 leukaemia.
Adv Exp Med Biol. 1986;195 Pt B:177-83. doi: 10.1007/978-1-4684-1248-2_27.
5
Biologic effect of 5-fluoro-2'-deoxyuridine incorporation in L1210 deoxyribonucleic acid.
Biochem Pharmacol. 1983 Apr 15;32(8):1337-40. doi: 10.1016/0006-2952(83)90443-4.
6
5-fluorouracil and 5-fluoro-2'-deoxyuridine follow different metabolic pathways in the induction of cell lethality in L1210 leukaemia.5-氟尿嘧啶和5-氟-2'-脱氧尿苷在诱导L1210白血病细胞致死性方面遵循不同的代谢途径。
Br J Cancer. 1984 Jun;49(6):739-44. doi: 10.1038/bjc.1984.116.
7
Incorporation of iododeoxyuridine-125-I into the DNA of L1210 leukemia cells during tumor development.在肿瘤发展过程中，碘脱氧尿苷-125-I掺入L1210白血病细胞的DNA中。
Cancer Res. 1970 Jan;30(1):236-43.
8
Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo.胸苷酸合成酶与二氢叶酸还原酶在体外和体内的相互作用。
Cancer Res. 1974 Jul;34(7):1619-26.
9
Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.对N10-炔丙基-5,8-二去氮叶酸（CB3717）产生获得性耐药的L1210细胞中胸苷酸合成酶增加：发育、特征及交叉耐药性研究
Cancer Res. 1986 Jun;46(6):2810-5.
10
In vivo effects of methotrexate. Inhibition of DNA synthesis and cell death in sensitive and resistant L1210 ascites populations.甲氨蝶呤的体内效应。对敏感和耐药L1210腹水细胞群DNA合成的抑制及细胞死亡。
Chemotherapy. 1972;17(1):59-70. doi: 10.1159/000220839.

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顺铂、大剂量注射氟尿嘧啶和亚叶酸钙用于晚期胃癌一线治疗，作为含氟尿嘧啶持续输注方案的替代方案。
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Cancers (Basel). 2011 Feb 17;3(1):675-99. doi: 10.3390/cancers3010675.
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An integrated analysis of the association between Ts gene polymorphisms and clinical outcome in gastric and colorectal cancer patients treated with 5-FU-based regimens.基于 5-FU 方案治疗的胃癌和结直肠癌患者中 Ts 基因多态性与临床结局的关联的综合分析。
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Functional interaction between fluorodeoxyuridine-induced cellular alterations and replication of a ribonucleotide reductase-negative herpes simplex virus.氟脱氧尿苷诱导的细胞改变与核糖核苷酸还原酶阴性单纯疱疹病毒复制之间的功能相互作用。
J Virol. 2001 Aug;75(15):7050-8. doi: 10.1128/JVI.75.15.7050-7058.2001.
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The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo.亚叶酸钙对5-氟尿嘧啶体外及体内抗人结肠癌细胞活性的调节作用。
Surg Today. 1993;23(7):615-20. doi: 10.1007/BF00311910.
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Sequential methotrexate/5-FU: FdUMP formation and TS inhibition in a transplantable rodent colon adenocarcinoma.序贯甲氨蝶呤/5-氟尿嘧啶：可移植性啮齿动物结肠腺癌中FdUMP的形成及胸苷酸合成酶抑制作用
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Experiments on the efficacy and toxicity of locoregional chemotherapy of liver tumors with 5-fluoro-2'-deoxyuridine (FUDR) and 5-fluorouracil (5-FU) in an animal model.在动物模型中对5-氟-2'-脱氧尿苷（FUDR）和5-氟尿嘧啶（5-FU）进行肝肿瘤局部区域化疗的疗效和毒性实验。
J Cancer Res Clin Oncol. 1986;111(1):42-6. doi: 10.1007/BF00402774.