The incorporation of 5-fluoro-2'-deoxyuridine into DNA of mammalian tumor cells.

Suppr

超能文献

作者信息

Danenberg P V, Heidelberger C, Mulkins M A, Peterson A R

出版信息

Biochem Biophys Res Commun. 1981 Sep 30;102(2):654-8. doi: 10.1016/s0006-291x(81)80182-9.

DOI:10.1016/s0006-291x(81)80182-9

PMID:6458299

Abstract

摘要

相似文献

The incorporation of 5-fluoro-2'-deoxyuridine into DNA of mammalian tumor cells.

Biochem Biophys Res Commun. 1981 Sep 30;102(2):654-8. doi: 10.1016/s0006-291x(81)80182-9.

5-Fluoro-2'-deoxyuridine incorporation in L1210 DNA.5-氟-2'-脱氧尿苷掺入L1210 DNA中。

J Biol Chem. 1981 Sep 10;256(17):8885-8.

Cytotoxicity of 5-fluoro-5'-O-nitro-2'-deoxyuridine, a new fluorinated pyrimidine derivative, in L1210 cultures.新型氟化嘧啶衍生物5-氟-5'-O-硝基-2'-脱氧尿苷在L1210细胞培养中的细胞毒性

Mol Pharmacol. 1982 Nov;22(3):760-5.

5-Fluoro-5'-deoxyuridine is an inhibitor of uridylate nucleotidase in L1210 leukaemia.

Adv Exp Med Biol. 1986;195 Pt B:177-83. doi: 10.1007/978-1-4684-1248-2_27.

Biologic effect of 5-fluoro-2'-deoxyuridine incorporation in L1210 deoxyribonucleic acid.

Biochem Pharmacol. 1983 Apr 15;32(8):1337-40. doi: 10.1016/0006-2952(83)90443-4.

5-fluorouracil and 5-fluoro-2'-deoxyuridine follow different metabolic pathways in the induction of cell lethality in L1210 leukaemia.5-氟尿嘧啶和5-氟-2'-脱氧尿苷在诱导L1210白血病细胞致死性方面遵循不同的代谢途径。

Br J Cancer. 1984 Jun;49(6):739-44. doi: 10.1038/bjc.1984.116.

Incorporation of iododeoxyuridine-125-I into the DNA of L1210 leukemia cells during tumor development.在肿瘤发展过程中，碘脱氧尿苷-125-I掺入L1210白血病细胞的DNA中。

Cancer Res. 1970 Jan;30(1):236-43.

Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo.胸苷酸合成酶与二氢叶酸还原酶在体外和体内的相互作用。

Cancer Res. 1974 Jul;34(7):1619-26.

Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.对N10-炔丙基-5,8-二去氮叶酸（CB3717）产生获得性耐药的L1210细胞中胸苷酸合成酶增加：发育、特征及交叉耐药性研究

Cancer Res. 1986 Jun;46(6):2810-5.

In vivo effects of methotrexate. Inhibition of DNA synthesis and cell death in sensitive and resistant L1210 ascites populations.甲氨蝶呤的体内效应。对敏感和耐药L1210腹水细胞群DNA合成的抑制及细胞死亡。

Chemotherapy. 1972;17(1):59-70. doi: 10.1159/000220839.

引用本文的文献

Novel insights into the role of translesion synthesis polymerase in DNA incorporation and bypass of 5-fluorouracil in colorectal cancer.新型研究揭示跨损伤合成聚合酶在结直肠癌中 5-氟尿嘧啶的 DNA 掺入和绕过中的作用。

Nucleic Acids Res. 2024 May 8;52(8):4295-4312. doi: 10.1093/nar/gkae102.

Adjusting the neuron to astrocyte ratio with cytostatics in hippocampal cell cultures from postnatal rats: A comparison of cytarabino furanoside (AraC) and 5-fluoro-2'-deoxyuridine (FUdR).用细胞抑制剂调整海马体培养物中神经元与星形胶质细胞的比例：阿糖胞苷（AraC）与 5-氟-2'-脱氧尿苷（FUdR）的比较。

PLoS One. 2022 Mar 9;17(3):e0265084. doi: 10.1371/journal.pone.0265084. eCollection 2022.

Cisplatin, Fluorouracil in Bolus Injection, and Leucovorin in First-Line Therapy for Advanced Gastric Cancer as an Alternative to Protocols With Infusional Fluorouracil.顺铂、大剂量注射氟尿嘧啶和亚叶酸钙用于晚期胃癌一线治疗，作为含氟尿嘧啶持续输注方案的替代方案。

J Glob Oncol. 2019 Jan;5:1-8. doi: 10.1200/JGO.18.00176.

Treatment of pancreatic cancer: what can we really predict today?胰腺癌的治疗：目前我们究竟能预测什么？

Cancers (Basel). 2011 Feb 17;3(1):675-99. doi: 10.3390/cancers3010675.

An integrated analysis of the association between Ts gene polymorphisms and clinical outcome in gastric and colorectal cancer patients treated with 5-FU-based regimens.基于 5-FU 方案治疗的胃癌和结直肠癌患者中 Ts 基因多态性与临床结局的关联的综合分析。

Mol Biol Rep. 2013 Jul;40(7):4637-44. doi: 10.1007/s11033-013-2557-8. Epub 2013 May 5.

Prognostic and predictive value of thymidylate synthase expression in colon cancer.胸苷酸合成酶表达在结肠癌中的预后及预测价值

Dig Dis Sci. 2008 May;53(5):1289-96. doi: 10.1007/s10620-007-0008-x. Epub 2007 Oct 13.

Functional interaction between fluorodeoxyuridine-induced cellular alterations and replication of a ribonucleotide reductase-negative herpes simplex virus.氟脱氧尿苷诱导的细胞改变与核糖核苷酸还原酶阴性单纯疱疹病毒复制之间的功能相互作用。

J Virol. 2001 Aug;75(15):7050-8. doi: 10.1128/JVI.75.15.7050-7058.2001.

The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo.亚叶酸钙对5-氟尿嘧啶体外及体内抗人结肠癌细胞活性的调节作用。

Surg Today. 1993;23(7):615-20. doi: 10.1007/BF00311910.

Sequential methotrexate/5-FU: FdUMP formation and TS inhibition in a transplantable rodent colon adenocarcinoma.序贯甲氨蝶呤/5-氟尿嘧啶：可移植性啮齿动物结肠腺癌中FdUMP的形成及胸苷酸合成酶抑制作用

Cancer Chemother Pharmacol. 1986;16(3):237-42. doi: 10.1007/BF00293984.

Experiments on the efficacy and toxicity of locoregional chemotherapy of liver tumors with 5-fluoro-2'-deoxyuridine (FUDR) and 5-fluorouracil (5-FU) in an animal model.在动物模型中对5-氟-2'-脱氧尿苷（FUDR）和5-氟尿嘧啶（5-FU）进行肝肿瘤局部区域化疗的疗效和毒性实验。

J Cancer Res Clin Oncol. 1986;111(1):42-6. doi: 10.1007/BF00402774.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验