Snitinskiĭ V V, Ianovich V G
Ukr Biokhim Zh (1978). 1981 Nov-Dec;53(6):45-9.
Hexokinase, glucokinase, phosphofructokinase, glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activity was studied in the liver and musculus quadriceps femoris of 110-day foetuses 1, 2, 3, 30 and 60-day piglets and in adult pigs. The activity of all enzymes in the tissues of newborn piglets is considerably higher than in the tissues of foetuses. The activity of hexokinase in both tissues of piglets increases in the first days after birth and lowers by the one month age. The phosphofructokinase activity in the skeletal muscles and the glucokinase one in the pig liver increase during the postnatal development. The activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in both tissues of pigs increases after birth and then decreases. Glucose metabolism in the pig liver at all stages of odontogenesis proceeds more intensively by the pentose phosphate pathway, and in the skeletal muscles--by glycolytic one.
研究了110天胎儿、1日龄、2日龄、3日龄、30日龄和60日龄仔猪以及成年猪肝脏和股四头肌中己糖激酶、葡萄糖激酶、磷酸果糖激酶、葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶的活性。新生仔猪组织中所有酶的活性均显著高于胎儿组织。仔猪两个组织中己糖激酶的活性在出生后的头几天增加,到1月龄时降低。骨骼肌中磷酸果糖激酶的活性和猪肝中葡萄糖激酶的活性在出生后发育过程中增加。猪两个组织中葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶的活性在出生后增加,然后降低。在牙齿发生的各个阶段,猪肝中的葡萄糖代谢通过磷酸戊糖途径进行得更为强烈,而在骨骼肌中则通过糖酵解途径进行。