Oakley G A
Vet Rec. 1981 Nov 28;109(22):485-7. doi: 10.1136/vr.109.22.485.
Single doses of 7.5 mg/kg levamisole subcutaneously and 5 mg/kg oxfendazole per os and three daily doses of diethylcarbamazine intramuscularly were 86.9, 82.1 and 46.6 per cent efficient, respectively, against one-day-old Dictyocaulus viviparus. These three dosage regimes were also associated, respectively, with 92.5, 36.4 and 56.0 per cent protection against reinfection following anthelmintic treatment. It is suggested that the high degree of protection following the use of levamisole may be a consequence of rapid and effective anthelmintic activity combined with immunomodulating effects.
皮下注射单剂量7.5毫克/千克的左旋咪唑、口服单剂量5毫克/千克的奥芬达唑以及肌肉注射三日剂量的乙胺嗪,分别对一日龄的胎生网尾线虫有86.9%、82.1%和46.6%的疗效。这三种给药方案在驱虫治疗后,分别还有92.5%、36.4%和56.0%的保护率防止再次感染。有人认为,使用左旋咪唑后有高度保护作用,可能是快速有效的驱虫活性与免疫调节作用相结合的结果。