Nilsson T
Acta Chir Scand. 1981;147(6):399-403.
An experimental investigation on rabbits was designed to determine which closure technique, single-layer or double-layer, gave the most secure closure of abdominal wall wounds. Interrupt Prolene sutures size 6-0 were used, and the wounds were tested mechanically in a materials testing machine on the 6th, 15th and 56th day after wounding. The results showed that the double-layer closed wound had, when tested after removal of sutures, a greater strength and higher energy absorption compared to the single-layer closed wound, which however had, when tested with sutures in situ, greater strength and higher energy absorption in the early post-operative phase. The possible explanations of these observations are discussed. Extrapolating from the animal experiments to the clinical situation, it can be concluded, that the double-layer technique was not to be preferred to the single-layer technique when securing a wound against rupture.
设计了一项针对兔子的实验研究，以确定哪种缝合技术（单层或双层）能最牢固地闭合腹壁伤口。使用6-0号间断普理灵缝线，在受伤后的第6天、第15天和第56天，在材料试验机上对伤口进行力学测试。结果表明，与单层闭合伤口相比，拆除缝线后测试时，双层闭合伤口具有更大的强度和更高的能量吸收能力；然而，在术后早期，当缝线仍在位时进行测试，单层闭合伤口具有更大的强度和更高的能量吸收能力。讨论了对这些观察结果的可能解释。从动物实验推断临床情况，可以得出结论，在防止伤口破裂方面，双层技术并不比单层技术更可取。
