通过错误导向的DNA合成进行位点特异性诱变。 - Suppr

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超能文献

Site-specific mutagenesis by error-directed DNA synthesis.

作者信息

Zakour R A, Loeb L A

出版信息

Nature. 1982 Feb 25;295(5851):708-10. doi: 10.1038/295708a0.

DOI:10.1038/295708a0

PMID:6460194

Abstract

摘要

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Site-specific mutagenesis by error-directed DNA synthesis.通过错误导向的DNA合成进行位点特异性诱变。

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Interactions between DNA polymerase and aminofluorene adducts that affect the recognition and possibly the mutagenicity of the lesions.DNA聚合酶与氨基芴加合物之间的相互作用，这种相互作用会影响损伤的识别以及可能的致突变性。

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Infidelity of DNA synthesis as a cause of mutagenesis.DNA合成错误作为诱变的一个原因。

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The role of DNA polymerase in base substitution mutagenesis on non-instructional templates.DNA聚合酶在非指导性模板上碱基置换诱变中的作用。

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Misincorporation during DNA synthesis, analyzed by gel electrophoresis.通过凝胶电泳分析DNA合成过程中的错误掺入。

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Site specific mutagenesis: insertion of single noncomplementary nucleotides at specified sites by error-directed DNA polymerization.位点特异性诱变：通过错向DNA聚合在特定位点插入单个非互补核苷酸。

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