Häggmark T, Jansson E, Eriksson E
Int J Sports Med. 1981 Feb;2(1):12-7. doi: 10.1055/s-2008-1034577.
The muscle atrophy of the quadriceps muscle was investigated in patients after knee operations and immobilization in a long leg plaster cast. Muscle biopsies were taken before operation and after 5 weeks immobilization. The activity of oxidative (SDH) and glycolytic (PFK) enzymes was determined. The fiber area of the different fiber types were measured and enzyme activities in single characterized fibers were analyzed. A selective type 1 atrophy was found with a reduced cross-cut area of the type 1 fiber, and a reduced oxidative enzyme activity occurred in the slow-twitch type 1 fibers. The effect of the muscle tension in the immobilized leg and the inhibiting role of the postoperative pain is discussed.
对膝关节手术后长期使用长腿石膏固定的患者的股四头肌萎缩情况进行了研究。在手术前和固定5周后进行肌肉活检。测定了氧化（SDH）和糖酵解（PFK）酶的活性。测量了不同纤维类型的纤维面积，并分析了单个特征性纤维中的酶活性。发现存在选择性的1型萎缩，1型纤维的横截面积减小，慢肌1型纤维中的氧化酶活性降低。讨论了固定腿部肌肉张力的影响以及术后疼痛的抑制作用。
