Simpson J B, Baim D S, Robert E W, Harrison D C
Am J Cardiol. 1982 Apr 1;49(5):1216-22. doi: 10.1016/0002-9149(82)90047-9.
A new catheter system has been designed for percutaneous transluminal coronary angioplasty. An independently movable, flexible-tipped guide wire within the balloon dilation catheter facilitates selection of the involved vessel. This guide wire can be passed slowly and carefully beyond the coronary stenosis, permitting safe advancement of the balloon catheter. After testing in animal and cadaver hearts, this system was used in 53 patients (56 stenoses) with single vessel coronary artery disease, with an overall primary success rate of 64 percent. In the last 41 of these 56 cases, use of a balloon catheter with a smaller deflated diameter increased the success rate to 73 percent. In patients with lesions of the left anterior descending coronary artery, the success rate was 89 percent. Three (6 percent) of the 53 patients had complications during coronary arterial dilation that necessitated emergency coronary arterial bypass graft surgery. There were no procedure-related or late cardiac deaths. During the mean follow-up period of 8 months (range 1 to 21), there were one late death (of noncardiac causes) and no late myocardial infarctions. Clinical status was persistently improved in 31 of the 36 patients who had successful dilation. The remaining five patients experienced restenosis at the angioplasty site and return of angina pectoris within 3 months of dilation. Two of these patients had repeat coronary angioplasty with restoration of asymptomatic status, and three had elective coronary bypass graft surgery.
一种用于经皮腔内冠状动脉成形术的新型导管系统已被设计出来。球囊扩张导管内有一根可独立移动、尖端灵活的导丝，便于选择受累血管。这根导丝可以缓慢而小心地穿过冠状动脉狭窄部位，使球囊导管能够安全推进。在动物和尸体心脏上进行测试后，该系统被用于53例（56处狭窄）单支冠状动脉疾病患者，总体首次成功率为64%。在这56例中的最后41例中，使用直径较小的未充气球囊导管使成功率提高到73%。在左前降支冠状动脉病变患者中，成功率为89%。53例患者中有3例（6%）在冠状动脉扩张过程中出现并发症，需要进行紧急冠状动脉旁路移植手术。没有与手术相关的或晚期心脏死亡病例。在平均8个月（范围1至21个月）的随访期内，有1例晚期死亡（非心脏原因），没有晚期心肌梗死病例。36例成功扩张的患者中有31例临床状况持续改善。其余5例患者在血管成形术部位出现再狭窄，并在扩张后3个月内再次出现心绞痛。其中2例患者接受了再次冠状动脉成形术，恢复到无症状状态，3例患者接受了择期冠状动脉旁路移植手术。
