Maisin J R
C R Seances Soc Biol Fil. 1982;176(1):68-72.
Our results demonstrate that mixtures of radioprotectors increase the degree of protection against the short and the long term effects compared with that obtained with each substance given separately. The most potent mixtures of radioprotectors (AET, MEA, Cyst, GSH, 5-HT) yield for the long term survival a dose reduction factor of 2.1. Pulmonary lesions are most often the cause of death in protected mice irradiated with 13.5 Gy or more. At the time of death signs of sclerosis and atrophy in several tissues are associated with these lung lesions in most mice and increase with dose and time after exposure. The tissues most affected are the kidney, the alimentary tract, the liver and the lymphoid tissues.
我们的结果表明，与单独给予每种物质相比，辐射防护剂混合物可提高对短期和长期效应的防护程度。最有效的辐射防护剂混合物（AET、MEA、胱氨酸、谷胱甘肽、5-羟色胺）使长期存活率的剂量降低因子达到2.1。肺部损伤通常是接受13.5 Gy或更高剂量辐射的受保护小鼠死亡的原因。在大多数小鼠中，死亡时几个组织的硬化和萎缩迹象与这些肺部损伤相关，并随剂量和照射后时间的增加而增加。受影响最严重的组织是肾脏、消化道、肝脏和淋巴组织。
