Hii V, Courtright J B
J Bacteriol. 1982 May;150(2):981-3. doi: 10.1128/jb.150.2.981-983.1982.
Neurospora crassa is able to use long-chain fatty acids as the sole carbon and energy source. After growth on oleate there was nearly a 10-fold induction of the acyl coenzyme A (CoA) synthetase and a fivefold increase in the activity of the 3-hydroxyacyl-CoA dehydrogenase. There was a slight induction of the enoyl-CoA hydratase and 3-ketoacyl-CoA thiolase, but no apparent induction of the flavin-linked acyl-CoA dehydrogenase. These noncoordinate changes in the fatty acid degradation enzymes suggest that they are not organized into a multienzyme complex as is found in bacteria.
粗糙脉孢菌能够将长链脂肪酸作为唯一的碳源和能源。在油酸上生长后，酰基辅酶A（CoA）合成酶的诱导率接近10倍，3-羟酰基辅酶A脱氢酶的活性增加了5倍。烯酰辅酶A水合酶和3-酮酰辅酶A硫解酶有轻微诱导，但黄素连接的酰基辅酶A脱氢酶没有明显诱导。脂肪酸降解酶的这些非协同变化表明，它们不像在细菌中那样被组织成多酶复合物。
