Reinecke R K, De Villiers I L, Joubert G
Onderstepoort J Vet Res. 1984 Mar;51(1):33-9.
A recently established Eragrostis curvula pasture 1,1 ha in size at Hennops River in the Transvaal Highveld was contaminated from 6 October 1976 until 20 May 1977 by 30 weaned Merinos, each infested with 7 000 infective larvae of H. contortus. On 2 November 1976 3 groups of weaned Merinos and again on 10 January 1977 a further group of Merinos were infested with 40 000 infective larvae of Trichostrongylus axei. From 19 November a single group of sheep, predosed with T. axei, and a control group grazed with the seeders for 8 weeks. After 6 weeks another group of sheep dosed with T. axei grazed with them, thus ensuring a 2-week overlap. This continued until autumn, when the last groups were removed. Efficacy against challenge reached Class C (greater than 50% effective against total worm burdens of H. contortus in greater than 50% of sheep) in early summer and autumn, but only reached significant levels of either P less than 0,01 or P less than 0,05 in summer. Peak worm burdens in controls were recorded in early autumn.
位于德兰士瓦高草原亨诺普斯河畔的一片面积为1.1公顷、最近才建成的弯叶画眉草牧场,在1976年10月6日至1977年5月20日期间受到污染,30只断奶美利奴羊被放入其中,每只羊感染了7000条捻转血矛线虫感染性幼虫。1976年11月2日,3组断奶美利奴羊,以及在1977年1月10日又有一组美利奴羊,感染了40000条奥氏毛圆线虫感染性幼虫。从11月19日起,一组预先接种了奥氏毛圆线虫的羊和一个对照组与播种机一起放牧8周。6周后,另一组接种了奥氏毛圆线虫的羊与它们一起放牧,从而确保有2周的重叠期。这种情况一直持续到秋天,最后几组羊被移走。在初夏和秋季,对攻击的疗效达到C级(超过50%的羊对捻转血矛线虫的总虫负荷有效率超过50%),但在夏季仅达到P小于0.01或P小于0.05的显著水平。对照组的最高虫负荷记录在初秋。