Bouree P, Jerray M
Pathol Biol (Paris). 1984 Jun;32(5 Pt 2):651-3.
The authors report the evaluation of therapeutic efficiency of imidazole derivatives (flubendazole and mebendazole) against human larval cestoda. 31 patients were treated: 28 had hydatid cysts, 2 had alveolar echinococcosis, and 1 had cerebral cysticercosis. Results after several months follow-up (up to 6 years) show an arrest in development of lesions and absence of development of new cyst after leakage of hydatid fluid. Although interpretation of such results is difficult, imidazole derivatives seem efficient in high dosages (100 mg/kg), given over 1 or 2 years, without side effects.
作者报告了咪唑衍生物（氟苯达唑和甲苯达唑）对人体幼虫绦虫的治疗效果评估。共治疗了31例患者：28例患有包虫囊肿，2例患有肺泡型棘球蚴病，1例患有脑囊尾蚴病。经过数月随访（长达6年），结果显示病变发展停止，包虫液渗漏后无新囊肿形成。尽管对此类结果的解读存在困难，但咪唑衍生物在高剂量（100mg/kg）下给药1或2年似乎有效，且无副作用。
