Gale N, Rott T, Kambic V
Pathol Res Pract. 1984 May;178(5):454-60.
Rhabdomyoma is an extremely rare benign tumor originating from the skeletal or cardiac muscle cells. Only 87 cases of rhabdomyoma have been reported to date, 70% occurring in the head and neck areas. The authors present the fourth case of rhabdomyoma of the nasopharynx. The tumor appeared in an 18 year old woman with hypacusis. Examination of the epipharynx showed a 2 x 1,5 cm tumor, extending from torus tubarius down to the soft palate. Light microscopy disclosed areas and islands of polymorphous large cells with abundant eosinophilic cytoplasm. Cross striations were focally visible with special PTAH staining. Electron microscopy revealed parallel and haphazardly arranged fibrillar bands (myofibrils) with irregularly and periodically arranged densities corresponding to Z lines. The pecularities of our case were abundant cystically dilated rough endoplasmatic reticulum and the absence of cytoplasmatic glycogen.
横纹肌瘤是一种极其罕见的起源于骨骼肌或心肌细胞的良性肿瘤。迄今为止，仅报道过87例横纹肌瘤病例，其中70%发生于头颈部区域。本文作者报告了第四例鼻咽横纹肌瘤。该肿瘤出现在一名患有听力减退的18岁女性身上。上咽部检查发现一个2×1.5厘米的肿瘤，从咽鼓管圆枕向下延伸至软腭。光镜检查显示有多形性大细胞区域和细胞岛，细胞质丰富且呈嗜酸性。经特殊的磷钨酸苏木精（PTAH）染色后，可见局灶性横纹。电子显微镜检查显示有平行且杂乱排列的纤维带（肌原纤维），其密度不规则且周期性排列，对应于Z线。我们这例病例的特点是粗面内质网大量囊性扩张且细胞质中无糖原。
