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口服长效片剂形式的亚铁盐的生物制药评价。

Biopharmaceutical evaluation of ferrous salts in form of oral long-acting tablets.

作者信息

Krzyśko K, Bokowski W, Wichliński L M

出版信息

Pol J Pharmacol Pharm. 1984 Jan-Feb;36(1):73-7.

PMID:6462964
Abstract

We determined the relative bioavailability in men of two preparations containing ferrous salts in the form of long-action tablets in relation to analogous conventional preparations in the from of drops and tablets. The comparison of the bioavailability of preparations slowly and quickly releasing the active substance did not show any prolonged effect and greater absorption of drugs slowly releasing the active substance along the alimentary tract.

摘要

我们测定了两种长效片剂形式的含铁盐制剂在男性体内相对于滴剂和片剂形式的类似传统制剂的相对生物利用度。对缓慢和快速释放活性物质的制剂的生物利用度进行比较,未发现活性物质缓慢释放的药物在胃肠道中有任何延长作用和更大吸收。

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