Spruce B A, Baylis P H, Kerr D N, Morley A R
Postgrad Med J. 1984 Jul;60(705):493-4. doi: 10.1136/pgmj.60.705.493.
Renal tubular dysfunction may be recognized in patients suffering from urinary light chain disease or non-myelomatous hypergammaglobulinaemia. We report a patient who has the combination of distal renal tubular acidosis and nephrogenic diabetes insipidus in association with hypergammaglobulinaemia due solely to increased IgG. We postulate that the abnormalities of distal nephron function resulted from cell-mediated immune damage.
肾小管功能障碍可能在患有尿轻链病或非骨髓瘤性高球蛋白血症的患者中被识别出来。我们报告了一名患者,其仅因IgG增加而患有高球蛋白血症,并伴有远端肾小管酸中毒和肾性尿崩症。我们推测远端肾单位功能异常是由细胞介导的免疫损伤所致。