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饮食中的盐、脂肪和碳水化合物对大鼠液体和盐分摄入的影响。

Effects of dietary salt, fat, and carbohydrate on fluid and salt consumption of rats.

作者信息

Threatte R M, Quinn M R

出版信息

Proc Soc Exp Biol Med. 1984 Sep;176(4):476-84. doi: 10.3181/00379727-176-41901.

DOI:10.3181/00379727-176-41901
PMID:6463059
Abstract

Studies were conducted to investigate the influence of dietary sodium chloride (NaCl), fat, and carbohydrate on NaCl preferences of rats. Both long-term (48 hr) and short-term (20 min) two-bottle preference tests were used. Rats were fed either a basal salt (1.17%) diet or high salt (8.37 to 8.59%) diets in which the level of sucrose was modified by substitution with either corn oil or cornstarch. Water and NaCl consumption was measured in 48-hr two-bottle preference tests using various concentrations (0.005 to 0.5 M) of NaCl paired with water. The results of these studies suggest that changes in fluid consumption were accounted for by an increase in water consumption which was inversely related to the sucrose to starch ratio and directly related to the NaCl content of the diets. A reduction in NaCl consumption was observed only during the short-term (20 min) tests.

摘要

开展了多项研究以调查膳食氯化钠(NaCl)、脂肪和碳水化合物对大鼠NaCl偏好的影响。使用了长期(48小时)和短期(20分钟)的双瓶偏好测试。给大鼠喂食基础盐(1.17%)饮食或高盐(8.37%至8.59%)饮食,其中蔗糖水平通过用玉米油或玉米淀粉替代进行调整。在48小时双瓶偏好测试中,使用各种浓度(0.005至0.5M)的NaCl与水配对,测量水和NaCl的消耗量。这些研究结果表明,液体消耗量的变化是由水消耗量的增加引起的,水消耗量的增加与蔗糖与淀粉的比例呈负相关,与饮食中的NaCl含量呈正相关。仅在短期(20分钟)测试中观察到NaCl消耗量减少。

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