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[通过对观察结果的统计研究对育龄期女性功能性多毛症和多毛的病因诊断的贡献(作者译)]

[Contribution to the etiologic diagnosis of hypertrichosis and hirsutism of functional origin in women during active genital life by statistical study of observations (author's transl)].

作者信息

Bonafé J L, Eizenberg G, Genthon P, Royer M, Derache P

出版信息

Ann Dermatol Venereol. 1978 Jan;105(1):23-9.

PMID:646307
Abstract

After a recall of the etiologies of hypertrichosis and hirsutism, a method of diagnosis limited to functional pathological cases, was established. Having 31 complete case reports of functional hirsutism or hypertrichosis in women whose diagnosis--ovarian dystrophy or corticosuprarenal hyperplasia--was confirmed, the authors established a decision procedure based on the confrontation of two criteria obtained with a discriminant analysis program. These criteria included a clinical examination (intensity and localization of pilosity) and the effect of dexamethasone blockade on two plasmatic steroids, i. e., 17-hydroxyprogesterone and testosterone. The proposed diagnosis was furnished with a confidence index. 43 new cases confirmed the consistency between the clinical diagnosis and the automatic diagnosis.

摘要

在回顾多毛症和高雄激素血症的病因之后,建立了一种仅限于功能性病理病例的诊断方法。作者有31例功能性多毛症或多毛症女性的完整病例报告,其诊断——卵巢营养不良或肾上腺皮质增生——得到证实,作者基于通过判别分析程序获得的两个标准的对比建立了一个决策程序。这些标准包括临床检查(毛发的强度和分布部位)以及地塞米松阻断对两种血浆类固醇,即17-羟孕酮和睾酮的影响。所提出的诊断附有一个置信指数。43例新病例证实了临床诊断与自动诊断之间的一致性。

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