Caton M P, Coffee E C, Hambling D J, Hardy C J, Palfreyman M N
Prostaglandins. 1984 May;27(5):761-70. doi: 10.1016/0090-6980(84)90013-3.
Some (+)-11-deoxy-16-phenoxyprostaglandin E1 analogues have been evaluated as uterine stimulants in the anaesthetised pregnant rat. Gastrointestinal side effects, assessed by the antagonism of morphine-induced constipation in the mouse, were relatively low with some of these compounds, six of which had a much more favourable relative selectivity than 16,16-dimethyl-PGE2 methyl ester.
一些（+）-11-脱氧-16-苯氧基前列腺素E1类似物已在麻醉的妊娠大鼠中作为子宫兴奋剂进行了评估。通过小鼠吗啡诱导便秘的拮抗作用评估的胃肠道副作用，其中一些化合物相对较低，其中六种化合物的相对选择性比16,16-二甲基-PGE2甲酯更有利。
