Nuss D D, Aeling J L, Clemons D E, Weber W N
Arch Dermatol. 1978 May;114(5):743-6.
The four male patients with multiple hamartoma syndrome (Cowden's disease) in this report, have most of the previously reported findings associated with this syndrome and several important unreported findings that include multiple cutaneous trichilemmomas, cafe-au-lait spots, cutaneous squamous cell carcinoma, pathologic fracture, craniomegaly, probable malignant lung tumor, retinal glioma, drusens of the optic disk and retina, pseudotumor cerebri, mediastinal mass, and multiple small papillomatous lesions of the esophagus, stomach, and duodenum.
本报告中的四名患有多发性错构瘤综合征（考登病）的男性患者，具有此前报道的与该综合征相关的大多数表现，以及一些重要的未报道表现，包括多发性皮肤毛发上皮瘤、咖啡斑、皮肤鳞状细胞癌、病理性骨折、巨颅、可能的恶性肺肿瘤、视网膜胶质瘤、视盘和视网膜的玻璃膜疣、假性脑瘤、纵隔肿块，以及食管、胃和十二指肠的多发性小乳头状病变。
