伴有紫癜和冷性荨麻疹的原发性IgG冷球蛋白血症。
Essential IgG cryoglobulinemia with purpura and cold urticaria.
作者信息
Koda H, Kanaide A, Asahi M, Urabe H
出版信息
Arch Dermatol. 1978 May;114(5):784-6.
PMID:646404
Abstract
An 80-year-old woman with essential cryoglobulinemia developed recurrent, widespread, purpuric lesions with superficial skin ulcers and cold urticaria. No disorders of other organ systems were recognized. Attempts to transfer the cold sensitivity passively by serum and isolated cryoprecipitate of the patient were successful. Immunochemical studies showed that the cryoglobulin was composed of IgG only. It was suggested that the cryoprecipitate might not be due to immune complex formation in this case.
摘要
一名患有原发性冷球蛋白血症的80岁女性出现反复、广泛的紫癜性皮损，伴有浅表皮肤溃疡和寒冷性荨麻疹。未发现其他器官系统有病变。通过患者的血清和分离出的冷沉淀物被动转移冷敏感性的尝试获得成功。免疫化学研究表明，冷球蛋白仅由IgG组成。提示在这种情况下，冷沉淀物可能并非由免疫复合物形成所致。
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