Calandre L, Gomara S, Bermejo F, Millan J M, del Pozo G
Stroke. 1984 Jul-Aug;15(4):663-6. doi: 10.1161/01.str.15.4.663.
An approach to the controversy of the physiopathology and classification of ischemic stroke is attempted in this study. The computed tomographies (CT) of 88 patients with transient ischemic attacks (TIA), 46 with reversible ischemic neurologic deficits (RIND) and 70 with ischemic strokes with minimum residuum (SMR) are analysed. The incidence of focal ischemic lesions on CT is 25% in TIA and RIND and 35% in SMR, when the study was performed after the first 24 hours. The incidence of cerebral infarction was much lower when the CT was performed within the first 24 hours after the clinical event. No significant differences in size or location of the infarction were found between the different groups. Deep infarctions were smaller than superficial ones. TIA duration correlated neither with the incidence of CT abnormalities nor with the size of the lesions. No correlation was found between doppler or oculoplethysmography abnormalities, clinical groups and CT findings. In reference to the structural lesions that underlie the clinical syndromes, TIA, RIND and SMR should not be considered as different groups.
本研究尝试探讨缺血性中风的病理生理学及分类争议问题。分析了88例短暂性脑缺血发作（TIA）患者、46例可逆性缺血性神经功能缺损（RIND）患者和70例最小残留缺血性中风（SMR）患者的计算机断层扫描（CT）结果。在发病24小时后进行研究时，TIA和RIND患者CT上局灶性缺血性病变的发生率为25%，SMR患者为35%。在临床事件发生后的最初24小时内进行CT检查时，脑梗死的发生率要低得多。不同组之间梗死灶的大小和位置无显著差异。深部梗死灶比浅表梗死灶小。TIA持续时间与CT异常发生率及病变大小均无相关性。在多普勒或眼体积描记法异常、临床分组与CT检查结果之间未发现相关性。就构成临床综合征基础的结构性病变而言，TIA、RIND和SMR不应被视为不同的组别。
