Wilkins H A, Goll P H, Marshall T F, Moore P J
Trans R Soc Trop Med Hyg. 1984;78(2):216-21. doi: 10.1016/0035-9203(84)90281-5.
The roles of some of the factors thought to be responsible for the characteristic relationship between age and the intensity and prevalence of Schistosoma haematobium infection have been investigated. In this initial report a study population in an area of intense infection is described, as are the methods used. Subsequent papers report the effect of interrupting transmission with molluscicide in part of the area and compare changes in egg count in this treated area with changes in an area where no intervention took place. These allow a consideration of age-specific rates of loss and acquisition of infection to be made. The intensity and prevalence of infection varied between villages both in the treated and untreated areas, but the relation of age to the pattern of infection was regardless of the level of infection in the villages. Over-all, the number of subjects and their pattern of infection was similar in both areas. The prevalence of infection tended to be higher in adult males than females but preliminary water contact observations suggest males are less exposed to infection. Observations over the three-year study period emphasize the extent of population movement in the study area and point to its importance in the planning of control measures.
人们已经对一些被认为是导致年龄与埃及血吸虫感染强度及流行率之间特征性关系的因素所起的作用进行了研究。在这份初步报告中，描述了一个高度感染地区的研究人群以及所使用的方法。后续论文报告了在该地区部分区域使用杀螺剂阻断传播的效果，并将该处理区域的虫卵计数变化与未进行干预区域的变化进行了比较。这些使得能够对特定年龄的感染丧失率和获得率进行考量。在处理区和未处理区的村庄中，感染强度和流行率都有所不同，但年龄与感染模式的关系与村庄的感染水平无关。总体而言，两个区域的研究对象数量及其感染模式相似。感染流行率在成年男性中往往高于女性，但初步的与水接触观察表明男性接触感染的机会较少。在三年研究期内的观察结果强调了研究区域内人口流动的程度，并指出了其在控制措施规划中的重要性。
