Wells G A, Lewis G, Hawkins S A, Don P L
Vet Rec. 1984 Jun 30;114(26):631-5. doi: 10.1136/vr.114.26.631.
In a series of pig brains submitted from field cases where water deprivation/sodium salt intoxication was suspected, histopathological examinations and chloride determinations were performed. A poor correlation was found between brain chloride concentration and neuropathology. The ranges of chloride concentrations found were similar for brains showing the encephalopathy of water deprivation/sodium salt intoxication, brains with other neuropathological diagnoses and brains without significant histopathological lesions. A close correlation was found between brain sodium and chloride in a further similar series, suggesting that determinations of sodium would not be more helpful diagnostically than determinations of chloride. A wide range of brain chloride values was also found in a group of healthy slaughtered pigs but the significance of this was not apparent. Brain chloride determinations have little value in the diagnosis of water deprivation/sodium salt intoxication in pigs, especially when performed in isolation without concurrent neuropathology and an adequate clinical history.
在一系列来自疑似存在缺水/钠盐中毒的现场病例的猪脑中，进行了组织病理学检查和氯化物测定。发现脑氯化物浓度与神经病理学之间的相关性较差。对于表现出缺水/钠盐中毒性脑病的脑、具有其他神经病理学诊断的脑以及没有明显组织病理学病变的脑，所发现的氯化物浓度范围相似。在另一个相似的系列中，发现脑钠和氯化物之间存在密切相关性，这表明钠测定在诊断上并不比氯化物测定更有帮助。在一组健康屠宰猪中也发现了广泛的脑氯化物值范围，但其意义并不明显。脑氯化物测定在猪缺水/钠盐中毒的诊断中价值不大，特别是在没有并发神经病理学和充分临床病史的情况下单独进行时。
