Karsza A, Banyó T
Acta Chir Hung. 1984;25(2):87-95.
Authors investigated the degree of restoration of renal function in 30 patients after relief of unilateral obstruction of different duration and degree. In order to evaluate the renal function they investigated the distal-tubular functions. Separated renal function examinations were made with the help of nephrostomical catheters, which were inserted partly with diagnostical partly with therapeutical purposes. The same parameters of the opposite kidney served as control. After relief of obstruction the examinations were repeated weekly in order to evaluate the repair of renal function. Based on their results, it was established that the degree of glomerular filtration is unchanged even after a month. The concentrating and acidifying ability of the kidney showed a further tendency to repair as compared to the values measured a week after relief. Not even a parameter changed in the following period over a month. They have the opinion that, contrary to the results of animal experiments, the values measured after a week of relief of obstruction are not final ones. In most cases 3 or 4 weeks are necessary for the kidney to reach a constant renal function on the basis of which a definitive operation plan can be made.
作者对30例不同时长和程度的单侧梗阻解除后的患者肾功能恢复程度进行了研究。为评估肾功能，他们对远曲小管功能进行了研究。借助肾造瘘导管进行了单独的肾功能检查，插入导管部分用于诊断，部分用于治疗。对侧肾脏的相同参数作为对照。梗阻解除后，每周重复检查以评估肾功能的恢复情况。根据检查结果确定，即使在一个月后肾小球滤过率仍无变化。与梗阻解除一周后测得的值相比，肾脏的浓缩和酸化能力显示出进一步的恢复趋势。在接下来的一个月里，没有一个参数发生变化。他们认为，与动物实验结果相反，梗阻解除一周后测得的值并非最终值。在大多数情况下，肾脏需要3至4周才能达到稳定的肾功能，在此基础上才能制定明确的手术方案。
