Eide N, Skjeldal O
Acta Ophthalmol (Copenh). 1984 Jun;62(3):351-8. doi: 10.1111/j.1755-3768.1984.tb08414.x.
A case of neurosyphilis is described. The presenting symptoms were reduced vision and pain around the left eye. The examination revealed a juxtapapillary chorioretinitis and neurosyphilis with elevated total protein (0.84 g/l) and pleocytosis (250 cells X 10(6)/l) in the cerebrospinal fluid (CFS). Four months after treatment with penicillin for 10 days and prednisolone for 5 weeks, the ophthalmological signs had disappeared. There was no pleocytosis (4 cells X 10(6)/l), and the total protein content in CSF was almost normal (0.52 g/l). Treatment with 6 mill (IU) penicillin G intravenously every 6 h resulted in a concentration in serum and spinal fluid higher than the generally accepted treponemacidal level.
本文描述了一例神经梅毒病例。患者的主要症状为视力下降和左眼周围疼痛。检查发现有视乳头旁脉络膜视网膜炎以及神经梅毒,脑脊液中总蛋白升高(0.84g/l)且有细胞增多现象(250个细胞×10⁶/l)。在用青霉素治疗10天及泼尼松龙治疗5周后4个月,眼科体征消失。此时无细胞增多现象(4个细胞×10⁶/l),脑脊液中总蛋白含量几乎正常(0.52g/l)。每6小时静脉注射600万(国际单位)青霉素G,使得血清和脑脊液中的浓度高于普遍认可的杀梅毒螺旋体水平。