Bedell S E, Kang J L
Am J Med. 1984 Aug;77(2):345-6. doi: 10.1016/0002-9343(84)90718-6.
Fever is a well-known side effect of quinidine therapy, but an elevated white blood cell count is considered unusual. Two patients are described who had leukocytosis or a marked left shift in the white blood cell count (or both) in association with quinidine fever. Neither patient had evidence of infection. In each of these patients, the temperature and white blood cell count returned to normal within two days after quinidine was discontinued. Although infection should always be considered in a patient with fever, leukocytosis, and a left shift, these may also appear in association with quinidine therapy.
发热是奎尼丁治疗众所周知的副作用，但白细胞计数升高被认为不常见。本文描述了两名患者，他们在出现奎尼丁热的同时伴有白细胞增多或白细胞计数明显左移（或两者皆有）。两名患者均无感染证据。在停用奎尼丁后的两天内，每位患者的体温和白细胞计数均恢复正常。虽然对于发热、白细胞增多和左移的患者应始终考虑感染因素，但这些情况也可能与奎尼丁治疗有关。
