Hara T, Kishikawa T, Miyazaki S, Ishii E, Goya N
Am J Pediatr Hematol Oncol. 1984 Summer;6(2):129-36. doi: 10.1097/00043426-198406020-00003.
We used cranial computed tomography (CT) to evaluate 51 leukemic patients with or without central nervous system (CNS) symptoms. Among 17 symptomatic patients, nine had gross abnormalities on CT scans; leukemic infiltrations, infections (CNS aspergillosis), hemorrhages, and therapy-related complications were all evident. One with a leukemic infiltration showed a periventricular low density on the CT scans. The differential diagnosis of CT findings and the correlation between clinical and CT findings is described. The significance of a low-density area observed in an asymptomatic patient on long-term intrathecal methotrexate therapy for CNS leukemia is also discussed.
我们使用头颅计算机断层扫描（CT）对51例有或无中枢神经系统（CNS）症状的白血病患者进行评估。在17例有症状的患者中，9例CT扫描显示有明显异常；白血病浸润、感染（中枢神经系统曲霉菌病）、出血及治疗相关并发症均很明显。1例有白血病浸润的患者CT扫描显示脑室周围低密度影。描述了CT表现的鉴别诊断以及临床与CT表现之间的相关性。还讨论了在无症状患者中，长期鞘内注射甲氨蝶呤治疗中枢神经系统白血病时观察到的低密度区的意义。
