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[术前应激。术前未使用术前药患者的心理行为及生理应激参数研究]

[Preoperative stress. Study of the mental behavior and parameters of physiological stress in non-premedicated patients during the preoperative period].

作者信息

Tolksdorf W, Berlin J, Rey E R, Schmidt R, Kollmeier W, Storz W, Ridder T, Schaetzle P

出版信息

Anaesthesist. 1984 May;33(5):212-7.

PMID:6465509
Abstract

In 29 male patients undergoing arterial bypass operations of the lower limb, psychological and physiological stress parameters were investigated. They received no premedication. We found an increase of heart rate (HR), arterial blood pressure (BP), plasma cortisol (Cort), free fatty acids (FFA), ventricular ectopic beats (VEB) and supra-ventricular ectopic beats (SVEB) (registered with a 24 hour ECG). The physiological dynamics were different, depending on the results of the psychological tests (MMQ and ESB): Repressor had higher HR and increased significantly more than sensitizer. Depressive patients had higher Cort levels the day before surgery compared to hopeful ones, but remained at these levels, whereas hopeful patients had a significant increase of Cort immediately before operation. They had also higher BP's and HR's. Patients with sthenic affections increased significantly more with FFA levels than asthenic ones. Anxious and asthenic patients had significantly more VEB than non anxious and sthenic ones. These results can well be interpreted in terms of dynamic psychophysiological stress reactions. We propose the use of psychological and physiological stress parameters for investigations of methods for the reduction of preoperative stress.

摘要

在29例接受下肢动脉搭桥手术的男性患者中,对其心理和生理应激参数进行了研究。他们未接受术前用药。我们发现心率(HR)、动脉血压(BP)、血浆皮质醇(Cort)、游离脂肪酸(FFA)、室性异位搏动(VEB)和室上性异位搏动(SVEB)(通过24小时心电图记录)均有所增加。生理动态变化因心理测试(MMQ和ESB)结果而异:压抑型患者心率较高,且增幅明显大于敏感型患者。与充满希望的患者相比,抑郁患者在手术前一天的皮质醇水平较高,但保持在这些水平,而充满希望的患者在手术前即刻皮质醇水平显著升高。他们的血压和心率也较高。精力充沛型患者的游离脂肪酸水平增幅明显高于虚弱型患者。焦虑和虚弱型患者的室性异位搏动明显多于非焦虑和精力充沛型患者。这些结果可以很好地用动态心理生理应激反应来解释。我们建议使用心理和生理应激参数来研究减轻术前应激的方法。

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