Sanders A B, Kern K B, Ewy G A, Atlas M, Bailey L
Ann Emerg Med. 1984 Sep;13(9 Pt 1):672-5. doi: 10.1016/s0196-0644(84)80723-4.
A study was done to assess the effect of open-chest massage on resuscitation from cardiac arrest. Ten mongrel dogs weighing 20.3 +/- 3.2 kg were fibrillated electrically. Cardiopulmonary resuscitation (CPR) was initiated and continued for 15 minutes. Half the dogs with coronary perfusion pressures less than 30 mm Hg underwent thoracotomy and internal cardiac massage for three minutes. Closed-chest massage was continued with the other dogs. All dogs were defibrillated at 19 minutes, and resuscitation was determined at 20 minutes after defibrillation. None of the dogs in the closed-chest massage group was resuscitated successfully. Four of the five dogs that underwent open cardiac massage were resuscitated. Significant differences in aortic pressures and coronary perfusion pressures were noted for the first two minutes of open-chest massage (P less than .05). The results of this study indicate that resuscitation may be improved using open-chest massage when closed-chest massage fails to produce an adequate coronary perfusion pressure.
一项研究旨在评估开胸按摩对心脏骤停复苏的效果。选用10只体重为20.3±3.2千克的杂种狗，使其发生心室颤动。开始进行心肺复苏（CPR）并持续15分钟。冠状动脉灌注压低于30毫米汞柱的半数狗接受开胸手术并进行3分钟的心内按摩。其余的狗继续进行闭胸按摩。所有狗在19分钟时进行除颤，并在除颤后20分钟确定复苏情况。闭胸按摩组的狗均未成功复苏。接受开胸心脏按摩的5只狗中有4只复苏成功。开胸按摩的前两分钟，主动脉压和冠状动脉灌注压存在显著差异（P＜0.05）。本研究结果表明，当闭胸按摩未能产生足够的冠状动脉灌注压时，使用开胸按摩可能会改善复苏情况。
