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辅助性术后化疗后乳腺癌复发中的淋巴细胞亚群及反应性

Lymphocyte subpopulations and reactivity in breast cancer recurrence following adjuvant postoperative chemotherapy.

作者信息

Petrini B, Rotstein S, Blomgren H, Wasserman J, Baral E

出版信息

Anticancer Res. 1984 May-Jun;4(3):151-6.

PMID:6465853
Abstract

The size of various subset of blood lymphocytes and stimulations with PHA and allogeneic cells (MLC) were examined in 45 women with breast cancer receiving postoperative adjuvant cyclic chemotherapy with chlorambucil, methotrexate, and 5-fluorouracil (LMF). The patients who remained disease-free (n = 19) and those who relapsed (n = 26) during a 4.5 to 6-year follow-up period had similar initial values; and similar kinetics of the examined immunological parameters during and following completion of treatment.

摘要

对45例接受苯丁酸氮芥、甲氨蝶呤和5-氟尿嘧啶(LMF)术后辅助循环化疗的乳腺癌女性患者,检测了各种血液淋巴细胞亚群的大小以及用植物血凝素(PHA)和同种异体细胞(混合淋巴细胞培养,MLC)刺激后的情况。在4.5至6年的随访期内,无疾病复发的患者(n = 19)和复发的患者(n = 26)初始值相似;治疗期间及治疗结束后,所检测的免疫参数动力学也相似。

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