Lampert M H, Gerber L H, Glatstein E, Rosenberg S A, Danoff J V
Arch Phys Med Rehabil. 1984 Aug;65(8):477-80.
Functional outcome was evaluated in 40 patients with a diagnosis of soft tissue sarcoma (STS), who had received wide local surgical excision and postoperative radiation therapy. All patients were two or more years postsurgical excision, and 1.75 or more years postradiation. Patients were separated into three anatomic groups: head, neck, or trunk (HNT); lower extremity (LE); and upper extremity (UE). Each patient was assessed for range of motion, muscle strength, edema, pain, activities of daily living (ADL), and vocational changes. There was significantly more (p = 0.037) edema in patients with LE lesions than in patients in either of the other groups. Patients with LE lesions had greater difficulty with ADL and mobility than those with UE or HNT lesions (p = 0.019), and vocational changes were more frequent (p = 0.055). Patients with lower extremity STS are at higher risk for developing disability than patients with STS at other anatomic sites.
对40例诊断为软组织肉瘤（STS）且接受了广泛局部手术切除及术后放疗的患者进行了功能转归评估。所有患者术后切除已达两年或更长时间，放疗后已达1.75年或更长时间。患者被分为三个解剖学组：头颈部或躯干（HNT）；下肢（LE）；以及上肢（UE）。对每位患者的活动范围、肌肉力量、水肿、疼痛、日常生活活动能力（ADL）和职业变化进行了评估。与其他两组中的任何一组患者相比，LE病变患者的水肿明显更多（p = 0.037）。与UE或HNT病变患者相比，LE病变患者在ADL和活动能力方面存在更大困难（p = 0.019），职业变化也更频繁（p = 0.055）。与其他解剖部位的STS患者相比，下肢STS患者发生残疾的风险更高。
