Aznaurian A V, Akopdzhanian E S, Chilingarian S Ts
Arkh Anat Gistol Embriol. 1984 Apr;86(4):45-7.
By means of fluorescent method biogenic amines in the thymus tissue basophils have been investigated in intact and immunized rats and, simultaneously, in the peripheral blood of the immunized animals the hemolysins titer has been defined as an index of the immune response of the organism. In the immunized rats the number of the tissue basophils is increasing, there are many degranulated forms among them. Hence, the antigenic stimulation facilitates to the tissue basophils secretory activation, which is morphologically manifested as their degranulation. The hemolysins titer level in the peripheral blood is gradually decreasing, as the time of immunization increases. The content of biogenic amines in the tissue basophils does not undergo similar changes.
通过荧光法,对完整和免疫大鼠胸腺组织嗜碱性粒细胞中的生物胺进行了研究,同时,在免疫动物的外周血中,溶血素滴度被确定为机体免疫反应的指标。在免疫大鼠中,组织嗜碱性粒细胞数量增加,其中有许多脱颗粒形式。因此,抗原刺激促进了组织嗜碱性粒细胞的分泌激活,这在形态上表现为它们的脱颗粒。随着免疫时间的增加,外周血中溶血素滴度水平逐渐降低。组织嗜碱性粒细胞中生物胺的含量没有发生类似变化。