Capone R R, Sarfeh I J, Wong P Y
Arch Surg. 1978 May;113(5):646-9. doi: 10.1001/archsurg.1978.01370170108023.
Renal salt and water handling were studied in a patient who had refractory ascites that were due to alcoholic liver disease. The patient underwent a peritoneojugular shunt that was followed eight weeks later by a portacaval shunt. Ingestion of a 10-mEq sodium diet and albumin infusion had no effect on sodium balance but increased free water clearance before and after the operative procedures. After peritoneojugular shunt, free water clearance and sodium excretion increased. After portacaval shunt, free water clearance decreased and sodium retention occurred.
对一名因酒精性肝病导致顽固性腹水的患者的肾脏盐和水代谢进行了研究。该患者接受了腹腔颈静脉分流术,八周后又接受了门腔静脉分流术。摄入10毫当量钠饮食和输注白蛋白对钠平衡无影响,但在手术前后增加了自由水清除率。腹腔颈静脉分流术后,自由水清除率和钠排泄增加。门腔静脉分流术后,自由水清除率降低,出现钠潴留。