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三倍体、部分性葡萄胎与双精子受精。12例病例的调查研究。

Triploidy, partial mole and dispermy. An investigation of 12 cases.

作者信息

Procter S E, Gray E S, Watt J L

出版信息

Clin Genet. 1984 Jul;26(1):46-51. doi: 10.1111/j.1399-0004.1984.tb00787.x.

Abstract

Twelve triploid abortuses were investigated to determine the origin of the additional haploid set and were retrospectively examined for the development of partial hydatidiform mole. Eight out of ten suitable triploids were diagnosed as partial mole. Dispermy was indicated as the cause of triploidy in 6 informative cases of which 3 were also partial moles. However, one diandric triploid had no features of partial mole. The problem of maternal cell contamination in triploids and the difficulty of diagnosing partial moles on pathological grounds alone are discussed.

摘要

对12例三倍体流产胎儿进行研究,以确定额外单倍体组的来源,并对部分葡萄胎的发展情况进行回顾性检查。在10例合适的三倍体中,有8例被诊断为部分性葡萄胎。在6例可提供信息的三倍体病例中,双精子受精被认为是三倍体的病因,其中3例也是部分性葡萄胎。然而,有一个双雄三倍体没有部分性葡萄胎的特征。文中讨论了三倍体中母源细胞污染的问题以及仅基于病理依据诊断部分性葡萄胎的困难。

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