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睁眼后地松鼠视网膜光谱机制的发育

Development of spectral mechanisms in the ground squirrel retina following lid opening.

作者信息

Jacobs G H, Neitz J

出版信息

Exp Brain Res. 1984;55(3):507-14. doi: 10.1007/BF00235281.

DOI:10.1007/BF00235281
PMID:6468555
Abstract

The retina of the California ground squirrel (Spermophilus beecheyi) contains three classes of photopigments (lambda max = 440, 500, 525 nm). From optic nerve recordings it was previously discovered that the effectiveness of signals from the 440 nm cone increase gradually over the weeks following lid opening. In this experiment several features of the electroretinogram (ERG) were examined to assess developmental changes in signals originating in the outer retina. As judged by threshold sensitivity, suprathreshold responsivity, or adaptability, the contribution of the 525 nm mechanism reaches its adult level two to three weeks after lid opening. The 500 nm mechanism appears to have a similar developmental time course. The development of the 440 nm mechanism was tracked using a chromatic adaptation measure. So indexed, the time required for this mechanism to reach its adult status was much greater than that for the other two mechanisms (70-80 days vs 40-45 days of age). The relatively slow development of effectiveness of the 440 spectral mechanism appears to reflect events occurring in the outer retina.

摘要

加利福尼亚地松鼠(Spermophilus beecheyi)的视网膜含有三类光色素(最大吸收波长 = 440、500、525纳米)。先前通过视神经记录发现,在睁眼后的数周内,来自440纳米视锥细胞的信号有效性逐渐增加。在本实验中,对视网膜电图(ERG)的几个特征进行了检查,以评估源自视网膜外层的信号的发育变化。根据阈值敏感性、阈上反应性或适应性判断,525纳米机制的贡献在睁眼后两到三周达到成年水平。500纳米机制似乎具有相似的发育时间进程。使用颜色适应测量来追踪440纳米机制的发育。以此指标衡量,该机制达到成年状态所需的时间比其他两种机制长得多(70 - 80天对比40 - 45日龄)。440光谱机制有效性的相对缓慢发育似乎反映了视网膜外层发生的事件。

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Exp Brain Res. 1983;49(3):443-52. doi: 10.1007/BF00238785.
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