Smith D E, Downs I
Am J Anat. 1978 Apr;151(4):527-37. doi: 10.1002/aja.1001510407.
Newborn to 9-week-old kittens were anesthetized and then sacrificed by inserting a scalpel into the thoracic cavity and severing the descending aorta. The cerebella were removed and processed according to Golgi-Cox and rapid Golgi modifications. The results indicate that the dendritic processes of the granule cells undergo a marked postnatal maturation even though there is little postmigratory change in the size and shape of the cell body. A club-shaped swelling of the distal portions of the dendrites is observed by the end of the first week; this "claw" becomes multilobated by three weeks and displays elaborate digitiform projections by nine weeks. The sequence of postnatal development in the kitten appears to follow a time course similar to that observed in other species. A possible correlation between the postnatal development of the granule cell and the postnatal development of the spincocerebellar system is discussed.
将新生至9周龄的小猫麻醉，然后通过将手术刀插入胸腔并切断降主动脉来处死。取出小脑并按照高尔基-考克斯法和快速高尔基改良法进行处理。结果表明，尽管细胞体的大小和形状在迁移后变化不大，但颗粒细胞的树突状突起在出生后经历了显著的成熟过程。在第一周结束时观察到树突远端呈棒状肿胀；这种“爪”在三周时变成多叶状，并在九周时呈现出精细的指状突起。小猫出生后发育的顺序似乎遵循与其他物种相似的时间进程。文中讨论了颗粒细胞出生后发育与脊髓小脑系统出生后发育之间可能的相关性。
