通过超速起搏成功治疗因室性心动过速导致的复发性奎尼丁晕厥。

Successful treatment by overdrive pacing of recurrent quinidine syncope due to ventricular tachycardia.

作者信息

Anderson J L, Mason J W

出版信息

Am J Med. 1978 Apr;64(4):715-8. doi: 10.1016/0002-9343(78)90595-8.

Abstract

A 54 year old patient who experienced recurrent ventricular tachycardia subsequent to quinidine administration for conversion of atrial fibrillation is described. Over a 10 hour period, 25 sustained episodes of ventricular tachycardia occurred for which electrical cardioversion was required in addition to numerous self-terminating paroxysms. Medical therapy with lidocaine, procainamide and propranolol was unsuccessful in controlling the arrhythmia. However, placement of a transvenous right ventricular pacemaker with overdrive pacing at a rate of 110 beats/min abrupty terminated all further ventricular ectopic activity during the period of quinidine elimination. Temporary overdrive pacing may be the treatment of choice for refractory, recurrent, ventricular tachycardia associated with quinidine therapy.

摘要

本文描述了一名54岁患者，在使用奎尼丁转复房颤后出现复发性室性心动过速。在10小时内，发生了25次持续性室性心动过速发作，除了许多自行终止的阵发性发作外，还需要进行电复律。利多卡因、普鲁卡因胺和普萘洛尔的药物治疗未能控制心律失常。然而，在奎尼丁清除期间，以110次/分钟的速率进行超速起搏的经静脉右心室起搏器的置入突然终止了所有进一步的室性异位活动。临时超速起搏可能是与奎尼丁治疗相关的难治性、复发性室性心动过速的首选治疗方法。