Leipzig B, Cummings C W
Head Neck Surg. 1984 Jul-Aug;6(6):992-7. doi: 10.1002/hed.2890060603.
A review of recent developments in experimental canine surgery using autogenous frozen grafts for mandibular reconstruction has elicited enthusiasm for their human application in cancer surgery. They do reossify, even under adverse conditions of perioperative irradiation, to regenerate a mandibular graft in the dog. Our experience with six patients who underwent immediate autogenous mandibular graft reconstruction is dismal. All failed because of intraoral complications; none evidenced recurrence of tumor in bone. A delayed procedure, in which revascularization of the midportion of the bone graft may be improved, may prevent many of these problems.
对近期使用自体冷冻移植物进行犬下颌骨重建的实验性手术进展的回顾引发了人们对其在癌症手术中应用于人类的热情。即使在围手术期放疗的不利条件下，它们也会重新骨化，从而在犬体内再生下颌骨移植物。我们对六例接受即刻自体下颌骨移植物重建的患者的经验并不乐观。所有病例均因口腔内并发症而失败；无一例显示骨内肿瘤复发。一种延迟手术，其中骨移植物中部的血管再生可能会得到改善，可能会避免许多此类问题。
