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盐酸马普替林与紧张性木僵临床状态及癫痫性脑电图相关。

Maprotiline hydrochloride associated with a clinical state of catatonic stupor and epileptic encephalogram.

作者信息

Atri P B, Julius D A

出版信息

J Clin Psychopharmacol. 1984 Aug;4(4):207-9.

PMID:6470193
Abstract

The authors describe a patient with major affective disorder, unipolar depressed type, recurrent, psychosis who went into a catatonic stupor state while being treated with maprotiline hydrochloride and thiothixene. The article also deals with findings on electroencephalogram, response to treatment, a review of other similar case reports, and the clinical significance and relevance based upon which other clinicians can take some precautionary measures while prescribing this newer antidepressant, especially in combination with a neuroleptic.

摘要

作者描述了一名患有复发性单相抑郁型重度情感障碍且伴有精神病性症状的患者,该患者在接受盐酸马普替林和硫利达嗪治疗时陷入紧张性木僵状态。文章还讨论了脑电图检查结果、治疗反应,回顾了其他类似病例报告,以及基于这些内容的临床意义和相关性,其他临床医生在开具这种新型抗抑郁药时,尤其是与抗精神病药联合使用时,可以据此采取一些预防措施。

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Effects of psychotropic drugs on seizure threshold.精神药物对癫痫发作阈值的影响。
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