McCarthy S M, Stark D D, Moss A A, Goldberg H I
J Comput Assist Tomogr. 1984 Oct;8(5):846-50. doi: 10.1097/00004728-198410000-00006.
Twenty-two patients with malignant carcinoid syndrome were evaluated with CT, the largest series to date. A mass representing the primary tumor or local adenopathy was identified in four patients, appearing as a homogeneous mass involving mesentery and bowel. In two other patients the primary was not identifiable by barium series, angiography, CT, or laparotomy. In the remaining 16 patients who were scanned after resection of the primary four had mesenteric thickening and five had adenopathy. Malignant ascites was present in seven of 21 patients. All hepatic metastases were hypodense on the precontrast study. The effect of contrast administration on lesion detectability was variable, obscuring at least one or more metastases in eight of 21 scans. We recommend noncontrast scans of the liver in patients in whom the number and size of metastases are critical to therapy.
22例恶性类癌综合征患者接受了CT检查,这是迄今为止规模最大的系列研究。4例患者发现有代表原发性肿瘤或局部淋巴结病变的肿块,表现为累及肠系膜和肠的均匀肿块。另外2例患者经钡剂造影、血管造影、CT或剖腹探查均未发现原发性肿瘤。其余16例在原发性肿瘤切除后接受扫描的患者中,4例有肠系膜增厚,5例有淋巴结病变。21例患者中有7例出现恶性腹水。在增强扫描前,所有肝转移灶均呈低密度。对比剂注射对病变检出的影响各不相同,21次扫描中有8次至少使一个或多个转移灶显示不清。对于转移灶的数量和大小对治疗至关重要的患者,我们建议进行肝脏平扫。