Takano T, Endo T, Saito H, Ida T, Tanaka K, Osaka S, Ikeshita M, Yamate N, Hayakawa H
Jpn Circ J. 1984 Jul;48(7):678-89. doi: 10.1253/jcj.48.678.
The effects of intraaortic balloon pumping (IABP) were studied in 91 patients with acute myocardial infarction complicated with cardiogenic shock (75 pts), ventricular septal perforation (VSP) (12 pts), and/or mitral regurgitation (MR) (4 pts). Out of 44 pts with cardiogenic shock in whom IABP was performed, 14 pts could not recover from cardiogenic shock, 6 pts became dependent on IABP and 13 pts survived (29.5%). In contrast, out of the remaining 31 pts with cardiogenic shock who did not undergo IABP because of inability to insert IABP catheter or other reasons and were treated medically, only 3 pts survived (9.7%, p less than 0.05). After the initiation of IABP, BPd, CI, SVI, SWI, TMG increased significantly, and HR, CVP, PCWP, TPR decreased significantly. Comparison of hemodynamic parameters after the initiation of IABP showed that SVI and SWI at 24 hours were higher and CVP lower in survivors. Out of 7 pts with VSP who underwent IABP 2 pts were operated and survived.
short-term mortality in pts with cardiogenic shock was significantly lower in IABP-treated group, hemodynamic parameters improved after IABP, survivors from cardiogenic shock had higher SVI, SWI, BPd, and lower CVP than non-survivors, patients with VSP and MR had worse prognosis in spite of IABP.
对91例急性心肌梗死合并心源性休克(75例)、室间隔穿孔(VSP,12例)和/或二尖瓣反流(MR,4例)的患者进行了主动脉内球囊反搏(IABP)效果研究。在接受IABP治疗的44例心源性休克患者中,14例未能从心源性休克中恢复,6例对IABP产生依赖,13例存活(29.5%)。相比之下,其余31例因无法插入IABP导管或其他原因未接受IABP而接受药物治疗的心源性休克患者中,仅3例存活(9.7%,P<0.05)。开始IABP后,舒张压(BPd)、心脏指数(CI)、每搏量指数(SVI)、每搏功指数(SWI)、心肌耗氧量(TMG)显著增加,心率(HR)、中心静脉压(CVP)、肺毛细血管楔压(PCWP)、总外周阻力(TPR)显著降低。IABP开始后血流动力学参数比较显示,存活者24小时时的SVI和SWI较高,CVP较低。在7例接受IABP的VSP患者中,2例接受手术并存活。
IABP治疗组心源性休克患者的短期死亡率显著降低,IABP后血流动力学参数改善,心源性休克存活者的SVI、SWI、BPd高于未存活者,CVP低于未存活者,尽管有IABP,VSP和MR患者的预后仍较差。