血管加压素与癫痫发作的点燃效应
Vasopressin and the kindling of seizures.
作者信息
Corcoran M E, Cain D P, Finlay J M, Gillis B J
出版信息
Life Sci. 1984 Aug 27;35(9):947-52. doi: 10.1016/0024-3205(84)90660-x.
PMID:6472059
Abstract
In an attempt to confirm a previous report that two intracerebroventricular injections of arginine-vasopressin (AVP) can kindle convulsive seizures, we injected AVP up to 14 times. Although behavioral and electrographic effects were observed, seizures failed to develop with any reliability. These results call into question the phenomenon of AVP kindling.
摘要
为了证实先前的一项报告，即两次脑室内注射精氨酸加压素（AVP）可引发惊厥性癫痫发作，我们注射了多达14次AVP。尽管观察到了行为和脑电图效应，但癫痫发作未能可靠地发生。这些结果对AVP点燃现象提出了质疑。
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