Bogdasarov Iu B, Sorokin A I, Narkevich B Ia, Zaĭtseva T I, Dmitrieva G D
Med Radiol (Mosk). 1984 Aug;29(8):9-13.
A total of 27 patients with central lung cancer and 43 patients with peripheral lung cancer of various sites were examined after surgical intervention on a multichannel unit using 133Xe. The regional distribution of alveolar ventilation and perfusion blood flow were evaluated in the preoperative period as well as at varying times after operation. Statistical analysis of the results has shown that a significant decrease in the ventilation and blood flow is observed in the zone with a focus of lesion in the preoperative period. At the same time even in the preoperative period of compensatory increase in the ventilation and blood flow occurs in the lower zone of the contralateral lung. An increase in the ventilation and blood flow in all the zones of the remaining lung is observed after pulmonectomy; lobectomy does not change pulmonary function and the operated lung does not regenerate its function. No distinctions in the regional values of the ventilation/perfusion ratio were revealed during treatment. Regional perfusion and ventilation are changed in one direction, their ratio and hence the gaseous composition of the blood remain unchanged.
对27例中央型肺癌患者和43例不同部位的周围型肺癌患者在手术后使用多通道装置用133Xe进行了检查。在术前以及术后不同时间评估了肺泡通气和灌注血流的区域分布。结果的统计分析表明，术前病变部位区域的通气和血流显著减少。同时，即使在术前，对侧肺下部区域也会出现通气和血流的代偿性增加。肺切除术后，余肺所有区域的通气和血流均增加；肺叶切除术不改变肺功能，手术侧肺功能也不会恢复。治疗期间未发现通气/灌注比值的区域值有差异。区域灌注和通气同向变化，它们的比值以及血液的气体成分保持不变。
