Tatsuta M, Yamamura H, Yamamoto R, Ichii M, Iishi H, Noguchi S
Oncology. 1984;41(5):328-30. doi: 10.1159/000225848.
The diagnostic accuracy of measurement of carcinoembryonic antigen (CEA) and of analysis of the cytological characteristics of pericardial fluid was assessed in 10 patients with benign pericarditis and 7 patients with malignant pericarditis. The mean CEA levels of pericardial fluid specimens from patients with malignant pericarditis were significantly higher than those from patients with benign pericarditis. However, a high CEA level was not seen in a specimen of pericardial fluid which contained nonepithelial tumor cells. Positive cytological findings were obtained in specimens of pericardial fluid from 85.7% of the patients with malignant pericarditis. Correct diagnosis of malignancy was made by CEA assay alone or by cytological examination alone in 85.7% of the patients examined, while a combination of these methods raised the diagnostic rate to 100%.
对10例良性心包炎患者和7例恶性心包炎患者评估了癌胚抗原（CEA）测量及心包液细胞学特征分析的诊断准确性。恶性心包炎患者心包液标本的平均CEA水平显著高于良性心包炎患者。然而，在不含上皮肿瘤细胞的心包液标本中未发现CEA水平升高。85.7%的恶性心包炎患者心包液标本细胞学检查呈阳性。在85.7%的受检患者中，单独通过CEA检测或单独通过细胞学检查即可正确诊断恶性肿瘤，而将这些方法联合使用可使诊断率提高到100%。
