Okamoto S, Handa H, Hashimoto N
Surg Neurol. 1984 Oct;22(4):335-40. doi: 10.1016/0090-3019(84)90135-6.
Distributions of cerebral aneurysms by site were compared statistically in 78 reported cases associated with arteriovenous malformation, including our five cases, and cases with solitary intracranial aneurysms without arteriovenous malformation. When the feeder of an arteriovenous malformation was one of the branches of anterior, middle, or posterior cerebral arteries, the aneurysms were located on these respective arteries much more frequently than expected in the general aneurysmal population. This was statistically significant. Our results strongly suggest that abnormal hemodynamic stresses on the arteries from which the feeders branch out to arteriovenous malformations play a significant role in the development of intracranial aneurysms on these arteries.
对包括我们的5例在内的78例报告的与动静脉畸形相关的病例以及无动静脉畸形的孤立性颅内动脉瘤病例，按部位对脑动脉瘤的分布进行了统计学比较。当动静脉畸形的供血动脉是大脑前动脉、大脑中动脉或大脑后动脉的分支之一时，动脉瘤位于这些相应动脉上的频率比一般动脉瘤人群预期的要高得多。这具有统计学意义。我们的结果有力地表明，从供血动脉分支到动静脉畸形的动脉上的异常血流动力学应力在这些动脉上颅内动脉瘤的形成中起重要作用。
