Hidiroglou M, Ho S K, Ivan M, Shearer D A
Can J Comp Med. 1978 Jan;42(1):100-7.
Four experiments were conducted to obtain information on the manganese (Mn) status of ewes, doe rabbits and dairy cows with cystic ovaries. Manganese was not concentrated specifically in any one tissue or organ but the use of 54Mn has indicated that the isotope was retained by the liver for a longer time. Significantly lower (P less than 0.01) levels of Mn were observed in the liver, kidney and blood of pregnant ewes fed a synthetic diet containing low levels (5 ppm) of Mn than those that were supplemented with 60 ppm Mn. It would appear that the determination of blood Mn concentration would provide a valuable diagnostic tool for the assessment of the Mn status of the pregnant ewe and could be more reliable than data based on tissue (liver, kidney, ovary) levels of Mn. The cortical stroma of dairy cows with cystic ovaries had lower Mn contents than those cows that were without cystic ovaries. The data on blood suggests that cystic ovaries cannot be diagnosed by blood Mn levels if Mn was indeed a contributing factor of the development of this condition. The doe rabbit responded to supplemental dietary Mn in a manner analogous to the ewes.
进行了四项实验，以获取有关患有卵巢囊肿的母羊、母兔和奶牛的锰（Mn）状况的信息。锰并非特异性地集中在任何一个组织或器官中，但使用54Mn表明该同位素在肝脏中保留的时间更长。与补充了60 ppm锰的母羊相比，饲喂含低水平（5 ppm）锰的合成日粮的怀孕母羊的肝脏、肾脏和血液中的锰水平显著降低（P小于0.01）。看来，测定血液中的锰浓度将为评估怀孕母羊的锰状况提供一种有价值的诊断工具，并且可能比基于组织（肝脏、肾脏、卵巢）锰水平的数据更可靠。患有卵巢囊肿的奶牛的皮质基质中的锰含量低于没有卵巢囊肿的奶牛。血液数据表明，如果锰确实是这种疾病发展的一个促成因素，那么卵巢囊肿不能通过血液中的锰水平来诊断。母兔对日粮中补充锰的反应与母羊类似。
