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[大鼠胎盘结缔组织区滋养层细胞繁殖的特征。II. 有丝分裂形态的倍性程度测定]

[Characteristics of trophoblast cell reproduction in the connective zone of the rat placenta. II. Determination of the degree of ploidy of mitotic shapes].

作者信息

Zybina E V, Zybina T G, Shteĭn G I

出版信息

Tsitologiia. 1984 May;26(5):531-6.

PMID:6474571
Abstract

Morphological and cytophotometric studies have been made on polyploidization of placenta connective zone cells. Measurement of the DNA content in mitotic figures show that within a period of development ranging from day 13 to day 14 the bulk of mitoses (up to 25%) become tetraploid and octaploid. This may suggest that polyploidization of placenta connective zone cells proceeds via incomplete polyploidizing mitoses. Among tetraploid and octaploid mitotic figures, there are those corresponding to all the mitotic stages, from prophase to telophase. Consequently, mitosis in tetraploid and octaploid cells can reach telophase. In such cases polyploidization is likely to follow the acytokinetic mitotic pattern. A question of a certain maximum level of polyploidy that may be reached by cells due to the incomplete mitosis is discussed.

摘要

已对胎盘连接区细胞的多倍体化进行了形态学和细胞光度学研究。对有丝分裂图像中DNA含量的测量表明,在发育的第13天至第14天期间,大部分有丝分裂(高达25%)会变成四倍体和八倍体。这可能表明胎盘连接区细胞的多倍体化是通过不完全多倍体化有丝分裂进行的。在四倍体和八倍体有丝分裂图像中,有对应于从前期到末期所有有丝分裂阶段的图像。因此,四倍体和八倍体细胞中的有丝分裂可以达到末期。在这种情况下,多倍体化可能遵循无胞质分裂的有丝分裂模式。讨论了由于不完全有丝分裂细胞可能达到的某种多倍体最大水平的问题。

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