Kotova I P
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(7):1024-7.
Pathomorphological studies of the degree and expansion of atherosclerotic changes in the cerebrospinal levels in cases of chronic occlusions of the abdominal aorta and the major arteries of the lower extremities revealed marked changes at various levels of section in 12 cases. The morphological changes were characterized by the degenerated architectonics of the spinal cord and by a reduction in its volume in the antero-posterior direction throughout its length. The following considerable histologic alterations were found: the neurones were in various stages of necrobiosis, the selective distribution of the tigroid substance of picnomorphic nature was observed, the axonal reaction was pronounced with central chromatolysis and a shift of the nucleus toward the periphery. There was also a focal fiber destruction in the area of the posterior cornua.
对腹主动脉和下肢主要动脉慢性闭塞病例中脑脊髓水平动脉粥样硬化病变程度及扩展情况的病理形态学研究显示，12例患者在不同切片水平均有明显变化。形态学变化的特征为脊髓结构退化，且整个长度在前后方向上体积减小。发现了以下显著的组织学改变：神经元处于不同程度的渐进性坏死阶段，观察到嗜碱性虎斑物质的选择性分布，轴突反应明显，伴有中央性染色质溶解和细胞核向周边移位。后角区域也存在局灶性纤维破坏。
