碘普罗胺。一种新型非离子型造影剂。
Iopromide. A new non-ionic contrast medium.
作者信息
Dawson P, Bradshaw A, Hill C
出版信息
Acta Radiol Diagn (Stockh). 1984;25(3):253-6. doi: 10.1177/028418518402500316.
PMID:6475563
Abstract
The new non-ionic contrast agent, iopromide (Schering) is comparable in osmolality and viscosity to the other recently developed low osmolality media, ionic and non-ionic. Its chemotoxicity, as assessed by protein binding, enzyme inhibition and effects on the coagulation cascade is significantly less than that of the conventional media and very similar to that of another established new non-ionic agent, iopamidol (Niopam, Bracco/Merck).
摘要
新型非离子型造影剂碘普罗胺（先灵公司生产）在渗透压和黏度方面与其他近期研发的低渗造影剂（包括离子型和非离子型）相当。通过蛋白质结合、酶抑制以及对凝血级联反应的影响评估，其化学毒性显著低于传统造影剂，与另一种已获认可的新型非离子型造影剂碘帕醇（尼欧帕，博莱科/默克公司生产）非常相似。
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