Bricker J T, Garson A, Gillette P C
Am J Dis Child. 1984 Sep;138(9):866-8. doi: 10.1001/archpedi.1984.02140470064021.
Hereditary prolongation of the Q-T interval is associated with ventricular dysrhythmias. Children with hereditary prolongation of the Q-T interval may have symptoms that seem related to a neurologic abnormality. Two families had members who had been treated with phenytoin sodium for seizures and had died suddenly when the medication was discontinued. Children in both families were found to have prolongation of the Q-T interval. A history of seizures or of seizures in the family may be an indication of hereditary prolongation of the Q-T interval.
遗传性Q-T间期延长与室性心律失常有关。患有遗传性Q-T间期延长的儿童可能有似乎与神经异常相关的症状。有两个家族的成员曾因癫痫接受苯妥英钠治疗,在停药后突然死亡。两个家族中的儿童均被发现有Q-T间期延长。癫痫病史或家族中存在癫痫可能是遗传性Q-T间期延长的一个指征。